ORIGINAL PAPER
Evaluation of the effectiveness of combined podiatric therapy using
essential oils in the topical treatment of toenail onychomycosis
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1
Department of Medicine and Health Sciences, Institute of Health, Academy of Applied Sciences, Nowy Targ, Poland
2
2Department of Practical Cosmetology and Skin Diagnostics, Faculty of Pharmaceutical Sciences in Sosnowiec, Medical University
of Silesia in Katowice, Sosnowiec, Poland
Submission date: 2025-06-06
Acceptance date: 2025-07-18
Online publication date: 2026-01-27
KEYWORDS
TOPICS
ABSTRACT
Introduction:
Mycotic infections are difficult to treat and often require long-term therapeutic regimens. Many authors believe
that topical therapy is at the forefront of nail disease treatment because of fewer side effects than combined therapy.
Aim of the research: The present study evaluated the efficacy of podiatric therapy using a blend of essential oils for the treatment
of toenail onychomycosis and the quality of life of patients.
Material and methods:
A randomised evaluation of the effectiveness of therapy on 40 patients with onychomycosis confirmed
by mycological examination was conducted in a podiatry office. The participants were randomly assigned to groups I
(experimental) and II (control). After cleaning the pathologically affected fragments of the nail plate, the patients in group
I received topical serum with essential oils twice a day.
Results:
A significant difference was observed in the effectiveness of the therapy after 5–6 months. Healthy nail growth was
observed in 45.0% (n = 9) of Group I patients after 3–4 months of essential oil therapy. In Group II, the corresponding proportions
increased over time but were lower than those in Group I at each follow-up visit (20.0%, n = 4). Quality of life scores
increased from 2.00 to 5.50 (median) on a scale of 1 to 7 in Group I, and from 2.20 ±0.95 to 4.00 ±1.30 on a scale of 1 to 7 in
Group II, respectively. Podiatric therapy improved nail appearance.
Conclusions:
The use of essential oil-based serum in combination with nail milling constitutes a suitable topical treatment
strategy and can be a safe additional therapy.
Conclusions:
The use of essential oil-based serum in combination with nail milling constitutes a suitable topical treatment strategy and can be a safe additional therapy.