ORIGINAL PAPER
Evaluation of the therapeutic efficacy of clindamycin in patients hospitalised with erysipelas
1
Department of the Medicine, School in São José do Rio Preto (FAMERP) and CNPq (National Council for Research and Development),
Brazil
2
Medicine School, São Jose do Rio Preto (FAMERP), Brazil
Submission date: 2016-05-25
Final revision date: 2017-02-28
Acceptance date: 2017-09-25
Publication date: 2017-12-31
Medical Studies 2017;33(4):259-261
KEYWORDS
TOPICS
ABSTRACT
Introduction: Erysipelas is an acute skin infection of a streptococcal-related aetiology. Penicillin is the first-line antibiotic in the treatment of erysipelas; however, a number of other antibiotics are used.
Aim of the research: To evaluate the clinical response of erysipelas to clindamycin in hospitalised patients.
Material and methods: A retrospective cohort study was performed of all patients hospitalised with erysipelas and treated with the antibiotic clindamycin in Hospital de Base, São José do Rio Preto between 2000 and 2008.
Results: The efficacy of this medication was evaluated. Failure of clinical treatment was detected in 4% of the 50 patients treated with clindamycin, but no failure was seen in 51 patients who were treated with clindamycin combined with other antibiotics.
Conclusions: Clindamycin is clinically efficacious (96%) to treat patients hospitalised for erysipelas. Clindamycin is a good therapeutic option.
Aim of the research: To evaluate the clinical response of erysipelas to clindamycin in hospitalised patients.
Material and methods: A retrospective cohort study was performed of all patients hospitalised with erysipelas and treated with the antibiotic clindamycin in Hospital de Base, São José do Rio Preto between 2000 and 2008.
Results: The efficacy of this medication was evaluated. Failure of clinical treatment was detected in 4% of the 50 patients treated with clindamycin, but no failure was seen in 51 patients who were treated with clindamycin combined with other antibiotics.
Conclusions: Clindamycin is clinically efficacious (96%) to treat patients hospitalised for erysipelas. Clindamycin is a good therapeutic option.
REFERENCES (10)
1.
Pereira de Godoy JM, Galacini Massari P, Yoshino Rosinha M, Marinelli Brandao R, Foroni Casas AL. Epidemiological data and comorbidities of 428 patients hospitalized with erysipelas. Angiology 2010; 61: 492-494.
2.
Erysipelas GE. Clinicopathological classification and terminology. Ann Dermatol Venereol 2001; 128: 307-311.
3.
Bonnetblanc JM, Bedane C. Erysipelas: recognition and management. Am J Clin Dermatol 2003; 4: 157-163.
4.
McNamara DR, Tleyjeh IM, Berbari EF, Lahr BD, Martinez JW, Mirzoyev SA, Baddour LM. Incidence of lower-extremity cellulitis: a population-based study in Olmsted county, Minnesota. Mayo Clin Proc 2007; 82: 817-821.
5.
Bishara J, Golan-Cohen A, Robenshtok E. Uso de antibióticos em pacientes com erisipela: um estudo retrospectivo. Isr Med Assoc J 2001; 3: 722-724.
6.
Stevens DL, Bisno AL, Chambers HF, Dellinger EP, Goldstein EJ, Gorbach SL, Hirschmann JV, Kaplan SL, Montoya JG, Wade JC. Practice guidelines for the diagnosis and management of skin and soft-tissue infections. Clin Infect Dis 2005; 41: 1373.
7.
Kilburn SA, Featherstone P, Higgins B, Brindle R. Interventions for cellulitis and erysipelas. Cochrane Database Syst Rev 2010; 6: CD004299.
8.
de Godoy JM, de Godoy MF, Valente A, Camacho EL, Paiva EV. Lymphoscintigraphic evaluation in patients after erysipelas. Lymphology 2000; 33: 177-180.
9.
Pereira De Godoy JM, Augusto Dos Santos R, Vilela Filho RA, Guerreiro Godoy Mde F. Erysipelas and ulcer of the legs in patients with lipolymphedema. Eur J Dermatol 2011; 21: 101-102.
10.
Rosinha MY, Massa PG, Brandão RM, Casas ALF. Prevalence of mortality in patients hospitalized due to erysipelas and related comorbidities. J Phlebol Lymphol 2010; 3: 8-10.
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| eISSN: | 2300-6722 |
| ISSN: | 1899-1874 |
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