REVIEW PAPER
Retinal artery occlusion and its association with stroke –
literature review
1
Department of Ophthalmology, Voivodeship Regional Hospital, Kielce, Poland Head of the Department: Michał Biskup MD
2
Collegium Medicum, Jan Kochanowski University, Kielce, Poland Head of the Collegium: Prof. Marianna Janion MD, PhD
3
Department of Vitreoretinal Surgery, Medical University of Lublin, Lublin, Poland Head of the Department: Prof. Jerzy Mackiewicz MD, PhD
4
1st Clinic of Cardiology and Electrotherapy, Swietokrzyskie Cardiology Centre, Kielce, Poland Head of the Clinic: Prof. Beata Wożakowska-Kapłon MD, PhD
5
Ophthalmology Clinic Boni Fratres Lodziensis, Lodz, Poland Head of the Clinic: Piotr Gozdek MD, PhD
Submission date: 2022-10-19
Final revision date: 2022-12-12
Acceptance date: 2023-01-06
Publication date: 2023-03-31
Corresponding author
Joanna Roskal-Wałek
Dr. Joanna Roskal-Wałek Department of Ophthalmology Voivodeship Regional Hospital Collegium Medicum Jan Kochanowski University Kielce, Poland
Dr. Joanna Roskal-Wałek Department of Ophthalmology Voivodeship Regional Hospital Collegium Medicum Jan Kochanowski University Kielce, Poland
Medical Studies 2023;39(1):55-64
KEYWORDS
TOPICS
ABSTRACT
Retinal artery occlusion (RAO) leads to acute retinal ischemia. Despite the low incidence rate of RAO, the occurrence of this condition has very important clinical implications. It is an emergency condition that requires urgent diagnostic evaluation and treatment. RAO is the ocular equivalent of acute cerebral ischemia. Patients with RAO have similar etiology and risk factors to patients with ischemic stroke and also are at high risk of subsequent cardiovascular events. However, the impact of RAO on the risk of a further ischemic stroke is still a matter of debate. Herein, we present a literature review on the relationship between RAO and stroke.
REFERENCES (43)
1.
Hayreh SS, Podhajsky PA, Zimmerman MB. Retinal artery occlusion: associated systemic and ophthalmic abnormalities. Ophthalmology 2009; 116: 1928-1936.
2.
Dattilo M, Newman NJ, Biousse V. Acute retinal arterial ischemia. Ann Eye Sci 2018; 3: 28.
3.
Callizo J, Feltgen N, Pantenburg S, Wolf A, Neubauer AS, Jurklies B, Wachter R, Schmoor C, Schumacher M, Junker B, Pielen A; European Assessment Group for Lysis in the Eye. Cardiovascular risk factors in central retinal artery occlusion: results of a prospective and standardized medical examination. Ophthalmology 2015; 122: 1881-1888.
4.
Hankey GJ, Slattery JM, Warlow CP. Prognosis and prognostic factors of retinal infarction: a prospective cohort study. BMJ 1991; 302: 499-504.
5.
Rim TH, Han J, Choi YS, Hwang SS, Lee CS, Lee SC, Kim SS. Retinal artery occlusion and the risk of stroke development: twelve-year nationwide cohort study. Stroke 2016; 47: 376-382.
6.
Hong JH, Sohn SI, Kwak J, Yoo J, Ahn SJ, Woo SJ, Jung C, Yum KS, Bae HJ, Chang JY, Jung JH, Lee JS, Han MK. Retinal artery occlusion and associated recurrent vascular risk with underlying etiologies. PLoS One 2017; 12: e0177663.
7.
Roskal-Wałek J, Wałek P, Biskup M, Sidło J, Cieśla E, Odrobina D, Mackiewicz J, Wożakowska-Kapłon B. Retinal artery occlusion and its impact on the incidence of stroke, myocardial infarction, and all-cause mortality during 12-year follow-up. J Clin Med 2022; 11: 4076.
8.
Schorr EM, Rossi KC, Stein LK, Park BL, Tuhrim S, Dhamoon MS. Characteristics and outcomes of retinal artery occlusion: nationally representative data. Stroke 2020; 51: 800-807.
9.
Chang YS, Chu CC, Weng SF, Chang C, Wang JJ, Jan RL. The risk of acute coronary syndrome after retinal artery occlusion: a population-based cohort study. Br J Ophthalmol 2015; 99: 227-231.
10.
Chang YS, Jan RL, Weng SF, Wang JJ, Chio CC, Wei FT, Chu CC. Retinal artery occlusion and the 3-year risk of stroke in Taiwan: a nationwide population-based study. Am J Ophthalmol 2012; 154: 645-652.
11.
Park SJ, Choi NK, Yang BR, Park KH, Lee J, Jung SY, Woo SJ. Risk and risk periods for stroke and acute myocardial infarction in patients with central retinal artery occlusion. Ophthalmology 2015; 122: 2336-2343.
12.
French DD, Margo CE, Greenberg PB. Ischemic stroke risk in medicare beneficiaries with central retinal artery occlusion: a retrospective cohort study. Ophthalmol Ther 2018; 7: 125-131.
13.
Lavin P, Patrylo M, Hollar M, Espaillat KB, Kirshner H, Schrag M. Stroke risk and risk factors in patients with central retinal artery occlusion. Am J Ophthalmol 2018; 196: 96-100.
14.
Lee J, Kim SW, Lee SC, Kwon OW, Kim YD, Byeon SH. Co-occurrence of acute retinal artery occlusion and acute ischemic stroke: diffusion-weighted magnetic resonance imaging study. Am J Ophthalmol 2014; 157: 1231-1238.
15.
Leisser C, Findl O. Rate of strokes 1 year after retinal artery occlusion with analysis of risk groups. European J Ophthalmol 2020; 30: 360-362.
16.
Lauda F, Neugebauer H, Reiber L, Jüttler E. Acute silent brain infarction in monocular visual loss of ischemic origin. Cerebrovasc Dis 2015; 40: 151-156.
17.
Shaikh IS, Elsamna ST, Zarbin MA, Bhagat N. Assessing the risk of stroke development following retinal artery occlusion. J Stroke Cerebrovasc Dis 2020; 29: 105002.
18.
Mir TA, Arham AZ, Fang W, Alqahtani F, Alkhouli M, Gallo J, Hinkle DM. Acute vascular ischemic events in patients with central retinal artery occlusion in the United States: a nationwide study 2003-2014. Am J Ophthalmol 2019; 200: 179-186.
19.
Scoles D, McGeehan B, VanderBeek BL. The association of stroke with central and branch retinal arterial occlusion. Eye 2022; 36: 835-843.
20.
Chodnicki KD, Tanke LB, Pulido JS, Hodge DO, Klaas JP, Olsen TW, Bhatti MT, Chen JJ. Stroke risk before and after central retinal artery occlusion: a population-based analysis. ophthalmology. 2022; 129: 203-208.
21.
Vestergaard N, Torp-Pedersen C, Vorum H, Aasbjerg K. Risk of stroke, myocardial infarction, and death among patients with retinal artery occlusion and the effect of antithrombotic treatment. Transl Vis Sci Technol 2021; 10: 2.
22.
Zhou Y, Zhu W, Wang C. Relationship between retinal vascular occlusions and incident cerebrovascular diseases: a systematic review and meta-analysis. Medicine 2016; 95: e4075.
23.
Fallico M, Lotery AJ, Longo A, Avitabile T, Bonfiglio V, Russo A, Murabito P, Palmucci S, Pulvirenti A, Reibaldi M. Risk of acute stroke in patients with retinal artery occlusion: a systematic review and meta-analysis. Eye 2020; 34: 683-689.
24.
Avery MB, Magal I, Kherani A, Mitha AP. Risk of stroke in patients with ocular arterial occlusive disorders: a retrospective Canadian study. J Am Heart Assoc 2019; 8: e010509.
25.
Sacco RL, Kasner SE, Broderick JP, Caplan LR, Connors JJ, Culebras A, Elkind MS, George MG, Hamdan AD, Higashida RT, Hoh BL, Janis LS, Kase CS, Kleindorfer DO, Lee JM, Moseley ME, Peterson ED, Turan TN, Valderra- ma AL, Vinters HV; American Heart Association Stroke Council, Council on Cardiovascular Surgery and Anesthesia; Council on Cardiovascular Radiology and Intervention; Council on Cardiovascular and Stroke Nursing; Council on Epidemiology and Prevention; Council on Peripheral Vascular Disease; Council on Nutrition, Physical Activity and Metabolism. An updated definition of stroke for the 21st century: a statement for healthcare professionals from the American Heart Association/American Stroke Association. Stroke 2013; 44: 2064-2089.
26.
American Academy of Ophthalmology. The patient with transient visual loss. In: 2017-2018 Basic and Clinical Science Course, Section 05: Neuro-Ophthalmology. American Academy of Ophthalmology:161-172.
27.
Biousse V, Nahab F, Newman NJ. Management of acute retinal ischemia: follow the guidelines! Ophthalmology 2018; 125: 1597-1607.
28.
Meer E, Scoles D, Hua P, McGeehan B, VanderBeek BL. Recent practice patterns in acute retinal artery occlusions in the United States. Ophthal Epidemiol 2022; 29: 696-702.
29.
Hayreh SS. Do patients with retinal artery occlusion need urgent neurologic evaluation? Am J Ophthalmol 2018; 196: 53-56.
30.
Hayreh SS, Zimmerman MB. Ocular arterial occlusive disorders and carotid artery disease. Ophthalmol Retina 2017; 1: 12-18.
31.
Laczynski DJ, Gallop J, Lyden SP, Bena J, Yuan A, Smo- lock CJ, Caputo FJ. Retinal artery occlusion does not portend an increased risk of stroke. J Vasc Surg 2020; 72: 198-203.
32.
Golsari A, Bittersohl D, Cheng B, Griem P, Beck C, Hassenstein A, Nedelmann M, Magnus T, Fiehler J, Gerloff C, Thomalla G. Silent brain infarctions and leukoaraiosis in patients with retinal ischemia: a prospective single-center observational study. Stroke 2017; 48: 1392-1396.
33.
Kim YD, Kim JY, Park YJ, Park SJ, Baik SH, Kang J, Jung C, Woo SJ. Cerebral magnetic resonance imaging of coincidental infarction and small vessel disease in retinal artery occlusion. Sci Rep 2021; 11: 864.
34.
Vermeer SE, Hollander M, van Dijk EJ, Hofman A, Koudstaal PJ, Breteler MM; Rotterdam Scan Study. Silent brain infarcts and white matter lesions increase stroke risk in the general population: the Rotterdam Scan Study. Stroke 2003; 34: 1126-1129.
35.
Finn C, Giambrone AE, Gialdini G, Delgado D, Barada- ran H, Kamel H, Gupta A. The association between carotid artery atherosclerosis and silent brain infarction: a systematic review and meta-analysis. J Stroke Cerebrovasc Dis 2017; 26: 1594-1601.
36.
Christiansen CB, Lip GY, Lamberts M, Gislason G, Torp-Pedersen C, Olesen JB. Retinal vein and artery occlusions: a risk factor for stroke in atrial fibrillation. J Thromb Haemost 2013; 11: 1485-1492.
37.
Bruno A, Jones WL, Austin JK, Carter S, Qualls C. Vascular outcome in men with asymptomatic retinal cholesterol emboli. A cohort study. Ann Intern Med 1995; 1224: 249-253.
39.
Staszewski J, Pruszczyk P. Diagnostyka udaru kardiogennego. Neurologia po Dyplomie 05/2015. https://www.podyplomie.pl/neur... (October 19, 2021).
40.
Roskal-Wałek J, Wałek P, Sidło J, Biskup J, Mackiewicz J, Wożakowska-Kapłon B. Relationship between atrial fibrillation and retinal artery occlusion: what we know now and how we can use it in clinical practice? Folia Cardiologica 2021; 16: 311-317.
41.
Janion-Sadowska A, Turek Ł, Dudek A, Andrychowski J, Sadowski M. Atrial fibrillation and atrial flutter – the state of the art. Part 1. Medical Studies 2021; 37: 151-161.
42.
Janion-Sadowska A, Turek Ł, Dudek A, Andrychowski J, Sadowski M. Atrial fibrillation and flutter – the state of the art. Part 2. Medical Studies 2021; 37: 239-249.
43.
Roskal-Wałek J, Wałek P, Biskup M, Odrobina D, Mackiewicz J, Głuszek S, Wożakowska-Kapłon B. Central and branch retinal artery occlusion-do they harbor the same risk of further ischemic events? J Clin Med 2021; 10: 3093.
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