Please ensure Javascript is enabled for purposes of website accessibility
REVIEW PAPER
Sudden cardiac death – what do we know and how do we prevent it?
 
More details
Hide details
 
Publication date: 2013-12-30
 
 
Medical Studies 2013;29(4):328-337
 
KEYWORDS
ABSTRACT
Sudden cardiac death (SCD) is an important clinical problem with a complex and multifactor background. Trends in its prevention have been dynamically developing over the last decades. Patients with ischemic heart disease, especially after myocardial infarction, represent the largest group at an elevated risk of SCD. Many congenital and hereditary diseases are associated with an increased risk of SCD, particularly among young people. Although far from perfect, left ventricular ejection fraction remains the only widely recognized, relatively objective and credible method of assessing the risk of SCD among patients with heart failure. Other methods for assessing the risk are waiting for the final confirmation of their usefulness in clinical trials. The implantable cardioverter-defibrillator (ICD) and its newer version – totally subcutaneous S-ICD – remain the most effective methods of SCD prevention. The only class of drugs with well-proven efficiency in most patients at risk of SCD is β-blockers.
REFERENCES (43)
1.

Katritsis DG, Josephson ME. Sudden cardiac death and implantable cardioverter defibrillators: two modern epidemics? Europace 2012; 14: 787-794.
 
2.

Zipes DP, Camm AJ, Borggrefe M et al. ACC/AHA/ESC 2006 guidelines for management of patients with ventricular arrhythmias and the prevention of sudden cardiac death – executive summary: A report of the American College of Cardiology/American Heart Association Task Force and the European Societ. Eur Heart J 2006; 27: 2099-2140.
 
3.

Chugh SS, Reinier K, Teodorescu C et al. Epidemiology of sudden cardiac death: clinical and research implications. Ther Ad Prog Cardiovasc Dis 2008; 51: 213-228.
 
4.

Albert CM, Chae CU, Grodstein F et al. Prospective study of sudden cardiac death among women in the United States. Circulation 2003; 107: 2096-2101.
 
5.

Aziz EF, Javed F, Pratap B et al. Strategies for the prevention and treatment of sudden cardiac death. Open Access Emerg Med 2010; 2010: 99-114.
 
6.

Shephard R, Semsarian C. Advances in the prevention of sudden cardiac death in the young. Ther Adv Cardiovasc Dis 2009; 3: 145-155.
 
7.

Christiaans I, van Engelen K, van Langen IM et al. Risk stratification for sudden cardiac death in hypertrophic cardiomyopathy: systematic review of clinical risk markers. Europace 2010; 12: 313-321.
 
8.

Choroby wewnętrzne. Stan wiedzy na rok 2010. Szczeklik A (ed.). Medycyna Praktyczna, Kraków 2010.
 
9.

Angelini P. Coronary artery anomalies: an entity in search of an identity. Circulation 2007; 115: 1296-1305.
 
10.

Eckart RE, Scoville SL, Campbell CL et al. Sudden death in young adults: a 25-year review of autopsies in military recruits. Ann Intern Med 2004; 141: 829-834.
 
11.

Frommelt PC. Congenital coronary artery abnormalities predisposing to sudden cardiac death. Pacing Clin Electrophysiol 2009; 32 Suppl. 2: S63-6.
 
12.

Brugada P, Brugada J. Right bundle branch block, persistent ST segment elevation and sudden cardiac death: a distinct clinical and electrocardiographic syndrome. A multicenter report. J Am Coll Cardiol 1992; 20: 1391-1396.
 
13.

Antzelevitch C, Brugada P, Borggrefe M et al. Brugada syndrome: report of the second consensus conference: endorsed by the Heart Rhythm Society and the European Heart Rhythm Association. Circulation 2005; 111: 659-670.
 
14.

Kołodziej M, Śledź J, Janion M. Zespół Brugadów – niedoceniana przyczyna zgonów u osób bez organicznej choroby serca. Kardiol Pol 2009; 67: 157-161.
 
15.

Richter S, Sarkozy A, Paparella G et al. Number of electrocardiogram leads displaying the diagnostic coved-type pattern in Brugada syndrome: a diagnostic consensus criterion to be revised. Eur Heart J 2010; 31: 1357-1364.
 
16.

Brugada P, Benito B, Brugada R et al. Brugada syndrome: update 2009. Hellenic J Cardiol 2009; 50: 352-372.
 
17.

Zareba W, Moss AJ, Schwartz PJ et al. Influence of genotype on the clinical course of the long-QT syndrome. International Long-QT Syndrome Registry Research Group. N Engl J Med 1998; 339: 960-965.
 
18.

Rautaharju PM, Zhou SH, Wong S et al. Sex differences in the evolution of the electrocardiographic QT interval with age. Can J Cardiol 1992; 8: 690-695.
 
19.

Locati EH, Zareba W, Moss AJ et al. Age- and sex-related differences in clinical manifestations in patients with congenital long-QT syndrome: findings from the International LQTS Registry. Circulation 1998; 97: 2237-2244.
 
20.

Alpert MA. Sudden cardiac arrest and sudden cardiac death on dialysis: epidemiology, evaluation, treatment, and prevention. Hemodial Int 2011; 15 Suppl 1: S22-S29.
 
21.

Budrejko S, Kozłowski D. Zespół wczesnej repolaryzacji – cichy zabójca? Kardiologia Oparta na Faktach 2010; 3: 280-286.
 
22.

Haïssaguerre M, Derval N, Sacher F et al. Sudden cardiac arrest associated with early repolarization. N Engl J Med 2008; 358: 2016-2023.
 
23.

Rosso R, Kogan E, Belhassen B et al. J-point elevation in survivors of primary ventricular fibrillation and matched control subjects: incidence and clinical significance. J Am Coll Cardiol 2008; 52: 1231-1238.
 
24.

Tikkanen JT, Anttonen O, Junttila MJ et al. Long-term outcome associated with early repolarization on electrocardiography. N Engl J Med 2009; 361: 2529-2537.
 
25.

Bianco M, Bria S, Gianfelici A et al. Does early repolarization in the athlete have analogies with the Brugada syndrome? Eur Heart J 2001; 22: 504-510.
 
26.

Janion M, Sadowski M, Sielski J et al. Pierwotna i wtórna profilaktyka nagłej śmierci sercowej. Pol Arch Med Wewn 2006; 115, 67-74.
 
27.

Curtis AB, Narasimha D. Arrhythmias in women. Clin Cardiol 2012; 35: 166-171.
 
28.

Cappato R, Smith WM, Hood MA et al. Subcutaneous chronic implantable defibrillation systems in humans. J Interv Card Electrophysiol 2012; 34: 325-332.
 
29.

Pedersen SS, Lambiase P, Boersma LV et al. Evaluation of factors impacting clinical outcome and cost effectiveness of the S-ICD: design and rationale of the EFFORTLESS S-ICD Registry. Pacing Clin Electrophysiol 2012; 35: 574-579.
 
30.

Zuern CS, Barthel P, Bauer A. Heart rate turbulence as risk-predictor after myocardial infarction. Front Physiol 2011; 2: 99.
 
31.

Chugh SS, Uy-Evanado A, Teodorescu C et al. Women have lower prevalence of structural heart disease as a precursor to sudden cardiac arrest: the Oregon Sudden Unexpected Death Study. J Am Coll Cardiol 2009; 54: 2006-2011.
 
32.

Camm J, Klein H, Nisam S. The cost of implantable defibrillators: perceptions and reality. Eur Heart J 2007; 28: 392-397.
 
33.

Bluzaite I, Brazdzionyte J, Zaliūnas R et al. QT dispersion and heart rate variability in sudden death risk stratification in patients with ischemic heart disease. Medicina (Kaunas) 2006; 42: 450-454.
 
34.

Somberg JC, Molnar J. Usefulness of QT dispersion as an electrocardiographically derived index. Am J Cardiol 2002; 89: 291-294.
 
35.

Garcia Ede V. T-wave alternans: reviewing the clinical performance, understanding limitations, characterizing methodologies. Ann Noninvasiv Electrocardiol 2008; 13: 401-420.
 
36.

Bloomfield DM, Steinman RC, Namerow PB et al. Microvolt T-wave alternans distinguishes between patients likely and patients not likely to benefit from implanted cardiac defibrillator therapy: a solution to the Multicenter Automatic Defibrillator Implantation Trial (MADIT) II conundrum. Circulation 2004; 110: 1885-1889.
 
37.

Santangeli P, Infusino F, Sgueglia GA et al. Ventricular late potentials: a critical overview and current applications. J Electrocardiol 2008; 41: 318-324.
 
38.

Schmidt G, Malik M, Barthel P. Heart-rate turbulence after ventricular premature beats as a predictor of mortality after acute myocardial infarction. Lancet 1999; 353: 1390-1396.
 
39.

Bauer A, Malik M, Schmidt G et al. Heart rate turbulence: standards of measurement, physiological interpretation, and clinical use: International Society for Holter and Noninvasive Electrophysiology Consensus. J Am Coll Cardiol 2008; 52: 1353-1365.
 
40.

Jurek S, Sredniawa B, Musialik-Łydka A et al. Heart rate turbulence – a new predictor of sudden cardiac death. Pol Merkur Lekarski 2000; 23: 55-59.
 
41.

Kleiger RE, Stein PK, Bigger JT Jr. Heart rate variability: measurement and clinical utility. Ann Noninv Electrocardiol 2005; 10: 88-101.
 
42.

Bauer A, Kantelhardt JW, Barthel P et al. Deceleration capacity of heart rate as a predictor of mortality after myocardial infarction: cohort study. Lancet 2006; 367: 1674-1681.
 
43.

Bauer A, Barthel P, Schneider R et al. Improved Stratification of Autonomic Regulation for risk prediction in post-infarction patients with preserved left ventricular function (ISAR-Risk). Eur Heart J 2009; 30: 576-583.
 
eISSN:2300-6722
ISSN:1899-1874
Journals System - logo
Scroll to top