REVIEW PAPER
The enteric nervous system in physiological and pathological conditions
1
Department of Anatomy, Collegium Medicum, Jan Kochanowski University, Kielce, Poland
2
Department of Clinical and Experimental Pathomorphology with Histology and Forensic Medicine Laboratory, Collegium Medicum, Jan Kochanowski University, Kielce, Poland
Submission date: 2024-06-12
Final revision date: 2024-07-05
Acceptance date: 2024-09-06
Publication date: 2025-06-30
Corresponding author
Grzegorz Wróbel
Grzegorz Wróbel Department of Clinical and Experimental Pathomorphology with Histology and Forensic Medicine Laboratory Collegium Medicum Jan Kochanowski University Kielce, Poland
Grzegorz Wróbel Department of Clinical and Experimental Pathomorphology with Histology and Forensic Medicine Laboratory Collegium Medicum Jan Kochanowski University Kielce, Poland
Medical Studies 2025;41(2):65-74
KEYWORDS
TOPICS
ABSTRACT
The enteric nervous system is a specific part of the autonomic nervous system, whose role is mainly concerned with ensuring the proper functioning of the gastrointestinal tract. Numerous scientific studies show that the enteric nervous system plays many roles: it is responsible for peristalsis of the gastrointestinal tract, controls gastric acid secretion, regulates fluid permeation through the lining epithelium, controls local blood flow, and interacts with the immune and endocrine systems of the gut. Enteric nervous system failure or dysfunction can cause a number of intestinal neuropathies. These can be congenital or acquired neuropathies including those accompanying other conditions such as gastroparesis, achalasia, Crohn’s disease, Chagas disease and many others, including neurodegenerative diseases. This article is a review of the literature and provides a comprehensive study of the enteric nervous system in normal conditions and numerous clinical conditions.
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| eISSN: | 2300-6722 |
| ISSN: | 1899-1874 |
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