The impact of COVID-19 on the course and possible initiation of ulcerative colitis.
1
Student Research Group at the Chair and Department of Pathomorphology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, Zabrze, Poland.
2
Department of Biomedicine and Environmental Reasearch, Institute of Biological Sciences, The John Paul II Catholic Unversity Of Lublin Konstantynów 1J, 20-708 Lublin, Poland
3
Department of Pathomorphology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, 3 Maja St. 13 41-800 Zabrze, Poland.
4
Collegium Medicum im. Dr Władysław Biegański, Jan Długosz University, Washington St. 4/8, 42-200 Częstochowa, Poland
These authors had equal contribution to this work
Submission date: 2025-02-20
Final revision date: 2025-09-04
Acceptance date: 2025-09-19
Online publication date: 2026-07-07
Corresponding author
Marcin Pieniak
Student Research Group at the Chair and Department of Pathomorphology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, Zabrze, Poland.
Student Research Group at the Chair and Department of Pathomorphology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, Zabrze, Poland.
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ABSTRACT
This review presents an analysis of the available scientific research concerning the impact of COVID-19 infection on the course of ulcerative colitis (UC). There are cases suggesting that SARS-CoV-2 infection may be associated with exacerbations of UC; however, establishing a direct cause-effect relationship remains difficult. The exacerbations observed in UC patients during the COVID-19 pandemic may be attributable to stress-related factors. In addition, infection in UC patients may lead to complications and therapeutic challenges. The available reports indicate a potential role of COVID-19 as a triggering factor for the development of UC. Although further research is required to elucidate the role of this infection in both the progression and initiation of UC, current data suggest its potential significance in symptom exacerbation and the triggering of autoimmune processes. Yet larger registry and longitudinal data suggest COVID-19 usually does not worsen UC long term.
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| eISSN: | 2300-6722 |
| ISSN: | 1899-1874 |
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